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Index > Protein center > GHR(Gene name) > Bovine
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  • GHR (Gene name),
  • Growth hormone receptor (Protein name ),  GHR_BOVIN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Gene name:
    GHR;
    Protein name:
    Growth hormone receptor(GH receptor);
    Alternative:
    Somatotropin receptor;
    Organism:
    Bovine (Bos taurus). 
    General Annotation
    Sub Unit:
    On growth hormone (GH) binding, forms homodimers and binds JAK2 via a box 1-containing domain (By similarity). Binding to SOCS3 inhibits JAK2 activation, binding to CIS and SOCS2 inhibits STAT5 activation.
    Function:
    The soluble form (GHBP) acts as a reservoir of growth hormone in plasma and may be a modulator/inhibitor of GH signaling.
    Subcellular Location:
    Cell membrane Single-pass type I membrane protein On growth hormone binding, GHR is ubiquitinated, internalized, down-regulated and transported into a degradative or non-degradative pathway.
    Protein Attributes:
    Sequence length:
    634
    Sequence:
    50:
    MDLWQLLLTL | AVAGSSDAFS | GSEATPAFLV | RASQSLQILY | PVLETNSSGN | 
    100:
    PKFTKCRSPE | LETFSCHWTD | GANHSLQSPG | SVQMFYIRRD | IQEWKECPDY | 
    150:
    VSAGENSCYF | NSSYTSVWTP | YCIKLTSNGG | IVDHKCFSVE | DIVQPDPPVG | 
    200:
    LNWTLLNISL | TEIHADILVK | WEPPPNTDVK | MGWIILEYEL | HYKELNETQW | 
    250:
    KMMDPLMVTS | VPMYSLRLDK | EYEVRVRTRQ | RNTEKYGKFS | EVLLITFPQM | 
    300:
    NPSACEEDFQ | FPWFLIIIFG | ILGLAVTLYL | LIFSKQQRIK | MLILPPVPVP | 
    350:
    KIKGIDPDLL | KEGKLEEVNT | ILAIHDNYKH | EFYNDDSWVE | FIELDIDDPD | 
    400:
    EKTEGSDTDR | LLSNDHEKSL | NIFGAKDDDS | GRTSCYEPDI | LEADFHVSDM | 
    450:
    CDGTSEVAQP | QRLKGEADIS | CLDQKNQNNS | PSNDAAPASQ | QPSVILVEEN | 
    500:
    KPRPLLIGGT | ESTHQAVHTQ | LSNPSSLANI | DFYAQVSDIT | PAGNVVLSPG | 
    550:
    QKNKTGNPQC | DTHPEVVTPC | QANFIVDNAY | FCEVDAKKYI | ALAPHVEAES | 
    600:
    HVEPSFNQED | IYITTESLTT | TAGRSGTAEH | VPSSEIPVPD | YTSIHIVQSP | 
    634:
    QGLVLNATAL | PLPDKEFLSS | CGYVSTDQLN | KIMP
    3D Structure:
    N/A
    Predicted Eptitope:
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    EIAab Sequence  Vaild Sequence:
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    Related Databases
    UniGene:
    String:
    SMR:
    UniGene:
    Pfam:
    Uniprot:
     
    FOR
    ELISA Kit for Bovine GH receptor
    Cat.:
    E1036h
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    MSDS:
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    Packing:
    96T
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    ELISA Kit for Bovine GH receptor
    Cat.:
    E1036p
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    MSDS:
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    Packing:
    96T
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    ELISA Kit for Bovine GH receptor
    Cat.:
    E1036m
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    Packing:
    96T
    ELISA Kit for Bovine GH receptor
    Cat.:
    E1036c
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    MSDS:
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    Packing:
    96T
    ELISA Kit for Bovine GH receptor
    Cat.:
    E1036d
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    MSDS:
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    96T
    ELISA Kit for Bovine GH receptor
    Cat.:
    E1036r
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    MSDS:
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    Packing:
    96T
    ELISA Kit for Bovine GH receptor
    MSDS:
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    ELISA Kit for Bovine GH receptor
    Cat.:
    E1036b
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    MSDS:
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    Packing:
    96T
    CLIA Kit for Bovine GH receptor
    Cat.:
    U1036d
    Price:
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    MSDS:
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    Packing:
    96T
    CLIA Kit for Bovine GH receptor
    Cat.:
    U1036r
    Price:
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    MSDS:
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    Packing:
    96T
    CLIA Kit for Bovine GH receptor
    Cat.:
    U1036c
    Price:
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    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Bovine GH receptor
    Cat.:
    U1036p
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Bovine GH receptor
    Cat.:
    U1036m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Bovine GH receptor
    Cat.:
    U1036b
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Bovine GH receptor
    Cat.:
    U1036h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Bovine GH receptor
    MSDS:
    Please sign in first.
    Polyclonal Antibody for Bovine GH receptor
    Cat.:
    P1036Rb-m
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Bovine GH receptor
    Cat.:
    P1036Rb-r
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Bovine GH receptor
    Polyclonal Antibody for Bovine GH receptor
    Cat.:
    P1036Rb-h
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Bovine GH receptor
    Polyclonal Antibody for Bovine GH receptor
    Polyclonal Antibody for Bovine GH receptor
    Polyclonal Antibody for Bovine GH receptor
    Monoclonal Antibody for Bovine GH receptor
    Monoclonal Antibody for Bovine GH receptor
    Monoclonal Antibody for Bovine GH receptor
    Monoclonal Antibody for Bovine GH receptor
    Monoclonal Antibody for Bovine GH receptor
    Monoclonal Antibody for Bovine GH receptor
    Monoclonal Antibody for Bovine GH receptor
    Monoclonal Antibody for Bovine GH receptor
    Protein for Bovine GH receptor
    Cat.:
    R1036h
    Price:
    Please sign in first.
    Packing:
    1mg
    Purity:
    >90%
    Protein for Bovine GH receptor
    Protein for Bovine GH receptor
    Protein for Bovine GH receptor
    Protein for Bovine GH receptor
    Protein for Bovine GH receptor
    Protein for Bovine GH receptor
    Protein for Bovine GH receptor

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    References
    1. 1.
      "Cloning and in vivo expression of bovine growth hormone receptor mRNA."
      Hauser S.D. , McGrath M.F. , Collier R.J. , Krivi G.G.
      Mol. Cell. Endocrinol.72:187-200(1990) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
      strain: Holstein.
      tissue: Liver.
    2. 2.
      "Expression of somatotropin receptor messenger ribonucleic acid in bovine tissues."
      Lucy M.C. , Boyd C.K. , Koenigsfeld A.T. , Okamura C.S.
      J. Dairy Sci.81:1889-1895(1998) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
      strain: Holstein.
      tissue: Liver.
    3. 3.
      "Functional expression of bovine growth hormone receptor."
      Zhou Y. , Jiang H.
      Submitted (2004-09) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
    4. 4.
      "Variants of the 5'-untranslated region of the bovine growth hormone receptor mRNA: isolation, expression and effects on translational efficiency."
      Jiang H. , Lucy M.C.
      Gene265:45-53(2001) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 1-14
    5. 5.
      "Polymorphism in exon 10 of the bovine GHR gene detected by PCR-DGGE."
      Ge W. , Davis M.E. , Hines H.C. , Irvin K.M.
      Anim. Genet.30:167-168(1999) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 470-634;VARIANT SER-519
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